Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/253851758?client_source=feed&format=rss
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Monday, October 8, 2012
EU contributes ? 10 million to UNICEF education ... - Europa
European Commission
MEMO
Brussels, 7 ctober 2012
EU contributes ? 10 million to UNICEF education programmes for children of Syrian refugees and host communities in Jordan
New donation of ? 4.6 million signed today to scale up support to refugees and host communities brings total EU contribution for education to ?10 million
AMMAN, 7 October, 2012 - The European Union (EU) donated a further ?4.6 million to UNICEF for emergency education programmes in Jordan, benefiting Syrian refugee children as well as children of host communities. This brings its total contribution to ?10 million this year. The announcement was made by Jos? Manuel Barroso, President of the European Commission, and Anthony Lake, UNICEF Executive Director, during a joint visit to the newly opened school at Za?atari refugee camp in northern Jordan.
"We have to ensure that families who have had to flee their country can live in decent conditions and that their children do not lose their right to education and to a brighter future,? President Barroso said. ?Investing in education is investing in the future. I am therefore glad that the EU can support schooling of Syrian refugee children in Zaatari."
The EU has been supporting access to school for vulnerable children already since last school-year including formal, informal and non-formal education and psychosocial support in hosting communities.
"These schools can become oases of physical and psychological peace for Syrian children who have experienced what no child should," said Anthony Lake, Executive Director of UNICEF. "Here they can play and learn and heal and be children again. EU support has helped make this possible."
Today?s donation helps Syrian refugee children in Jordan where they presently live: inside the refugee camps, and outside along with the children of the Jordanian communities hosting them.
It covers teacher training and salaries, school fees, text books, school equipment and refurbishment, psychosocial support for children in need and other costs related to school years 2011-2012 and 2012-2013.
The Za?atari camp school, which opened last week, can currently accommodate up to 2,200 students, although UNICEF is increasing capacity to 5,000 and will continue to work to meet growing needs in the camp.
About UNICEF
UNICEF works in 190 countries and territories to help children survive and thrive, from early childhood through adolescence. The world?s largest provider of vaccines for developing countries, UNICEF supports child health and nutrition, good water and sanitation, quality basic education for all boys and girls, and the protection of children from violence, exploitation, and AIDS. UNICEF is funded entirely by the voluntary contributions of individuals, businesses, foundations and governments. For more information about UNICEF and its work visit: http://www.unicef.org
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Saturday, October 6, 2012
94% Looper
All Critics (206) | Top Critics (41) | Fresh (193) | Rotten (13)
The reasoning behind all this may not reward prolonged inspection, but Johnson is smart enough to press onward with his plot, leaving us with neither the time nor the desire to linger over the logic ...
Writer-director Rian Johnson establishes himself as an original talent who clearly believes storytelling must prevail.
A mind-bending ride that is not afraid to slow down now and again, to explore themes of regret and redemption, solitude and sacrifice, love and loss. It's a movie worth seeing and, perhaps, going back to see again.
Looper has more heart than Brick and the 2008 con-man flick The Brothers Bloom. Both fine achievements, they could also be described as viscerally cerebral.
I'm a sucker for time-travel movies.
Looper felt to me like a maddening near-miss ...
It's complex enough that sci-fi fans can dig deeper over multiple viewings, but thrilling enough that casual viewers can take it all in with one watch.
...an above-average sci-fi tale.
Rian Johnson makes a loud, dark, highly stylized film that looks good but whose ideas do not really bear close examination.
Time travel makes sense in Looper because writer-director Rian Johnson keeps it on a short leash, not requiring enough manufactured logic to trip over later.
I don't know where you guys found that kid... Was it the same lab where they grew the Fannings?
Besides a challenging time-travel premise, a dark sense of humor, and some thrilling action scenes, Looper has the kind emotional weight that you wouldn't expect.
... Writer-director Rian Johnson never stops working, using the science-fiction setup and trappings to delve into the characters and give us a story with some real meat.
You don't need time-travel to spot a future cult classic.
It's just a shame that a smart, thoughtful movie like this is all too often the exception to mainstream sci/fi action fare rather than the rule.
Despite some big set pieces, it's the smaller emotional moments that get us thinking
For a time travel thriller, this film is remarkably free of head-scratching anomalies in the plot, instead concentrating on richly developed characters and goosebump-inducing action
Nothing less than an exceptionally satisfying piece of futuristic ingenuity with a great corps of actors. It will knock you out -- in any time zone.
A scintillating neo-noir gem of existential quandaries and inescapable fatalism.
Joseph Gordon-Levitt, the hardest working man in Hollywood for 2012, continues his journey to the A-List.
Best stay focused and avoid a loo break!
This all sounds a little too much like The Terminator, but Johnson keeps things moving and rings ingenious changes on familiar material ...
It might be confusing in its time-travel material, but is both entertaining and somewhat challenging by being so action-packed and loopy.
More Critic ReviewsSource: http://www.rottentomatoes.com/m/looper/
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Tuesday, October 2, 2012
New hope for taming triple-negative breast cancer
ScienceDaily (Oct. 1, 2012) ? Disease-free survival is short-lived for women with triple-negative breast cancer -- a form of the disease that doesn't respond to hormone drugs and becomes resistant to chemotherapy. Thankfully, a promising line of study in the School of Medicine at The University of Texas Health Science Center San Antonio suggests it is possible to fine-tune the properties of this fearsome cancer, making it more sensitive to treatment.
Once preclinical studies have been completed in coming months, this new approach should be ready to test in female patients, a scientist said.
The research focuses on molecules called microRNAs that occur naturally throughout the body. These molecules play an important role during development and in disease processes. "Some microRNAs suppress cancer while others promote it," said Behyar Zoghi, M.D., Ph.D., hematology-medical oncology fellow in the School of Medicine and first author of a study presented at the recent American Society of Clinical Oncology (ASCO) meeting in San Francisco.
"We identified microRNAs that can uniquely sensitize drug-resistant, triple-negative breast cancer to chemotherapy drugs such as paclitaxel," said senior author Manjeet Rao, Ph.D., assistant professor of cellular and structural biology and a principal investigator at the Greehey Children's Cancer Research Institute of the UT Health Science Center. The institute's researchers pursue novel understandings about biology that will apply to both pediatric and adult cancers.
In preclinical studies, the team injected microRNA into mice with established tumors. "The microRNA not only killed the cancer and didn't let it come back, but was also safe based on toxicity studies of the liver and other tissues," Dr. Rao said.
The microRNA, delivered along with chemo, conditions the tumor so that it responds to a much lower dose of the drug and many side effects are prevented.
"MicroRNAs are very stable and small in size, so theoretically we don't need a very complex delivery vehicle," Dr. Rao said. "Importantly, the microRNAs that we studied can be very good prognostic markers, as they are detected in blood serum and expressed at significantly different levels in patients when compared with healthy individuals."
He expects the preclinical work to soon be translated to a first-in-humans Phase I clinical trial at the Cancer Therapy & Research Center (CTRC) at the UT Health Science Center San Antonio. The CTRC is one of four National Cancer Institute-designated Cancer Centers in Texas.
The team reported this study in September at the ASCO meeting. It was one of four studies selected for review by ASCO on the day it was presented. School of Medicine collaborators were Ismail Jatoi; M.D., Ph.D; Peter Ravdin, M.D., Ph.D.; Boyce Oliver Jr., M.D.; Anand Karnad, M.D.; Alfredo Santillan, M.D., M.P.H.; J. Saadi Imam, Ph.D.; Yao-Fu Chang, Ph.D.; Subbarayalu Panneerdoss, Ph.D.; and Suresh Prajapati, M.S. As part of his research, Dr. Zoghi was selected to receive a Texas Society of Clinical Oncology Fellows Award.
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The above story is reprinted from materials provided by University of Texas Health Science Center at San Antonio.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/ON8g8VE0qdg/121002092843.htm
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Therapeutic time window important factor for cord blood cell transplantation after stoke
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Public release date: 1-Oct-2012[ | E-mail |
Share ] Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Putnam Valley, NY. (Oct. 1, 2012) A research team from Germany has found that optimal benefit and functional improvement for ischemic stroke results when human umbilical cord blood mononuclear cells (hUCB MNCs) are transplanted into rat stroke models within 72 hours of the stroke. Their study is published in the current issue of Cell Transplantation (21:6), now freely available on-line at: http://www.ingentaconnect.com/content/cog/ct/.
"Ischemic stroke is one of the most frequent causes of death and the most common reason for permanent disabilities in adults in industrialized nations," said Dr. Johannes Boltze, study corresponding-author from the University of Leipzig. "Despite recent research, treatment opportunities are limited and the only approved therapy to date must be administered within a narrow four and a half hour time window."
According to the authors there is a "strong demand for alternative strategies," and among those most recently studied is Cell Transplantation using neonatal or adult stem cells. Their study investigates the time-dependent efficacy of hUCB MNCs following experimental brain ischemia in rats. The emphasis of their study was exploring factors that impact on Cell Transplantation to derive the best outcomes, such as determining an appropriate transplantation time point, or window of opportunity.
The researchers transplanted hUCB MNCs into test animals at various time intervals following stroke, at four hours, 24 hours, 72 hours, 120 hours and at 14 days.
"Our results demonstrated that transplantation within a 72 hour time window resulted in an early improvement in functional recovery," said Dr. Boltze.
"The failure to induce sustained functional recovery, lesion reduction, and limitation of glial scaring in animals treated at 120 hours indicates the 72 hour time window as efficient for cell application."
The authors noted that administration of hUCB MNCs within the 72 hour window resulted not only in functional recovery but also a reduction in brain atrophy and in diminished glial scaring demonstrating the importance of this factor on the impact of umbilical cord blood Cell Transplantation. Later transplantation, at 14 days, showed no benefit.
"Our study shows that hUCB MNCs are a promising tool for acute stroke treatment, but require a comparatively early intervention in the subacute phase of stroke," concluded the authors.
"This research adds to a growing body of evidence supporting specific early time periods for repair of the brain, spinal cord, heart and other organs following acute injury and is very important in the development of regenerative therapies" said Dr. Paul R. Sanberg, Distinguished Professor of Neurosurgery and Brain Repair at the University of South Florida.
###
Contact: Dr. Johannes Boltze, Frauhofer-Institute for cell Therapy and Immunology, Perlickstr. 1, D-04103 Leipzig, Germany.
Tel. +49-341-97-25814
Fax. +49-341- 97-25829
Email: johannes.boltze@izi.fraunhofer.de
Citation: Boltze, J.; Schmidt, U. R.; Reich, D. M.; Kranz, A.; Reymann, K. G.; Strassburger, M.; Lobsien, D.; Wagner, D.-C.; Frschler, A.; Schbitz, W.-R. Determination of the Therapeutic Time Window for Human Umbilical Cord Blood Mononuclear Cell Transplantation Following Experimental Stroke in Rats. Cell Transplant. 21(6):1199-1211; 2012.
The Coeditor-in-chief's for Cell Transplantation are at the Diabetes Research Institute, University of Miami Miller School of Medicine and Center for Neuropsychiatry, China Medical University Hospital, TaiChung, Taiwan. Contact, Camillo Ricordi, MD at ricordi@miami.edu or Shinn-Zong Lin, MD, PhD at shinnzong@yahoo.com.tw or David Eve, PhD at celltransplantation@gmail.com
News release by Florida Science Communications www.sciencescribe.net
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 1-Oct-2012[ | E-mail |
Share ] Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Putnam Valley, NY. (Oct. 1, 2012) A research team from Germany has found that optimal benefit and functional improvement for ischemic stroke results when human umbilical cord blood mononuclear cells (hUCB MNCs) are transplanted into rat stroke models within 72 hours of the stroke. Their study is published in the current issue of Cell Transplantation (21:6), now freely available on-line at: http://www.ingentaconnect.com/content/cog/ct/.
"Ischemic stroke is one of the most frequent causes of death and the most common reason for permanent disabilities in adults in industrialized nations," said Dr. Johannes Boltze, study corresponding-author from the University of Leipzig. "Despite recent research, treatment opportunities are limited and the only approved therapy to date must be administered within a narrow four and a half hour time window."
According to the authors there is a "strong demand for alternative strategies," and among those most recently studied is Cell Transplantation using neonatal or adult stem cells. Their study investigates the time-dependent efficacy of hUCB MNCs following experimental brain ischemia in rats. The emphasis of their study was exploring factors that impact on Cell Transplantation to derive the best outcomes, such as determining an appropriate transplantation time point, or window of opportunity.
The researchers transplanted hUCB MNCs into test animals at various time intervals following stroke, at four hours, 24 hours, 72 hours, 120 hours and at 14 days.
"Our results demonstrated that transplantation within a 72 hour time window resulted in an early improvement in functional recovery," said Dr. Boltze.
"The failure to induce sustained functional recovery, lesion reduction, and limitation of glial scaring in animals treated at 120 hours indicates the 72 hour time window as efficient for cell application."
The authors noted that administration of hUCB MNCs within the 72 hour window resulted not only in functional recovery but also a reduction in brain atrophy and in diminished glial scaring demonstrating the importance of this factor on the impact of umbilical cord blood Cell Transplantation. Later transplantation, at 14 days, showed no benefit.
"Our study shows that hUCB MNCs are a promising tool for acute stroke treatment, but require a comparatively early intervention in the subacute phase of stroke," concluded the authors.
"This research adds to a growing body of evidence supporting specific early time periods for repair of the brain, spinal cord, heart and other organs following acute injury and is very important in the development of regenerative therapies" said Dr. Paul R. Sanberg, Distinguished Professor of Neurosurgery and Brain Repair at the University of South Florida.
###
Contact: Dr. Johannes Boltze, Frauhofer-Institute for cell Therapy and Immunology, Perlickstr. 1, D-04103 Leipzig, Germany.
Tel. +49-341-97-25814
Fax. +49-341- 97-25829
Email: johannes.boltze@izi.fraunhofer.de
Citation: Boltze, J.; Schmidt, U. R.; Reich, D. M.; Kranz, A.; Reymann, K. G.; Strassburger, M.; Lobsien, D.; Wagner, D.-C.; Frschler, A.; Schbitz, W.-R. Determination of the Therapeutic Time Window for Human Umbilical Cord Blood Mononuclear Cell Transplantation Following Experimental Stroke in Rats. Cell Transplant. 21(6):1199-1211; 2012.
The Coeditor-in-chief's for Cell Transplantation are at the Diabetes Research Institute, University of Miami Miller School of Medicine and Center for Neuropsychiatry, China Medical University Hospital, TaiChung, Taiwan. Contact, Camillo Ricordi, MD at ricordi@miami.edu or Shinn-Zong Lin, MD, PhD at shinnzong@yahoo.com.tw or David Eve, PhD at celltransplantation@gmail.com
News release by Florida Science Communications www.sciencescribe.net
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-10/ctco-ttw100112.php
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Ultrabooks not yet ultradesirable, says report
4 hrs.
Ultrabooks are supposed to help satisfy MacBook Air lust? ? by being thin, light Apple knockoffs for Windows users ? but so far this year, they've been priced too high and buyers aren't ready to bite, according to IHS iSuppli.?
The research firm expected 22 million ultrabooks would be shipped worldwide in 2012; now the firm says that number will be 10.3 million, and most of those will be in the last quarter of this year.
For 2013,?IHS iSuppli had forecast shipments?of 61 million ultrabooks;?now, it says, it's looking more like 44 million.
"So far, the PC industry has failed to create the kind of?buzz and excitement?among consumers that is required to propel ultrabooks into the mainstream," said?Craig Stice, senior principal analyst for compute platforms at IHS, in a statement.
"This is especially a problem amid all the hype surrounding media tablets and smartphones," he said, specifically citing the iPhone 5, Kindle Fire HD and Microsoft Surface tablet, due out next month. "When combined with other factors, including prohibitively high pricing, this means that ultrabook sales will not meet expectations in 2012."
"High pricing"???at around $1,000???is definitely an issue when standard laptops still can be bought for much less,?many of them budget-priced models?at $400 and $500.
"Ultrabooks need to get?more systems?down to the $600?price?range in order to hit the volume level needed to enter the mainstream, down from prices at the $1,000 level now," Stice said.?
"If ultrabooks?using the new?Windows 8?operating system?come close to the $600 to?$700?range next year, while adding in an attractive new consumer feature such as a touchscreen,?a good chance?exists?for strong sales in 2013. If not???and ultrabooks stay at the $1,000 level???their sales?will?continue to struggle in 2013?as they must compete against?lower-priced options, such as tablets and smartphones."
Check out Technolog, Gadgetbox, Digital Life and In-Game on?Facebook,?and on?Twitter, follow Suzanne Choney.
Source: http://www.nbcnews.com/technology/technolog/ultrabooks-not-yet-ultradesirable-says-report-6206726
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Monday, October 1, 2012
Russian church: Pussy Riot deserve mercy if repent
MOSCOW (AP) ? The Russian Orthodox Church on Sunday asked for clemency for three jailed members of the rock band Pussy Riot if they repent for their "punk prayer" for deliverance from President Vladimir Putin at Moscow's main cathedral, a statement that came a day before an appeal hearing and appeared to reflect a desire to put an end to the case that has caused an international outrage.
But it was unclear whether the women, who were sentenced to two years last month, would offer a penitence sought by the church and how much leniency a court may show. Putin has always been reluctant to avoid leaving an impression that he could bow to public pressure and has taken an increasingly tough line on dissent since his inauguration in May.
Monday's appeal hearing has caught their family members between hope and despair as they attempt to gauge from the words and actions of government and church officials whether the political tide will turn in their favor.
In Sunday's statement, the church reaffirmed its condemnation of the women's raucous stunt, saying such actions "can't be left unpunished." But it added that if the women show "penitence and reconsideration of their action," their words "shouldn't be left unnoticed."
Earlier this month, Russian Prime Minister Dmitry Medvedev said that keeping them in prison any longer would be "unproductive" ? a statement that encouraged hopes the appeals court could set them free. But skeptics said that ahead of the band members' conviction on charges of "hooliganism driven by religious hatred," Putin himself said the women should not be judged too harshly, raising similar hopes for their release that proved vain.
Nadezhda Tolokonnikova, 22, Maria Alekhina, 24, and Yekaterina Samutsevich, 30, were arrested in March after dancing and high-kicking at Moscow's Christ the Savior Cathedral as they pleaded with the Virgin Mary to save Russia from Putin, who was elected to a third presidential term two weeks later. They said during their trial in August that they were protesting the Russian Orthodox Church's support for Putin and didn't intend to offend religious believers.
Both the government and the church may have a strong interest in putting the Pussy Riot case behind them to avoid further damage at home and abroad.
The band members' imprisonment has come to symbolize intolerance of dissent in Putin's Russia and caused a strong international condemnation. Their cause has been taken up by celebrities and musicians, including Madonna and Paul McCartney, and protests have been held around the world.
Even some government loyalists criticized the harsh sentence, voicing concern about the church's interference in secular affairs and a growing repressive streak in the Kremlin's policies.
Since his inauguration in May, Putin has taken an increasingly tough stance against dissent in response to a series of massive winter protests against his 13-year rule.
Opposition activists have faced interrogations and searches, and the Kremlin-controlled parliament quickly stamped a slew of draconian bills, including the one that raised fines 150-fold for taking part in unsanctioned protests and another obliging those non-government organizations that receive foreign funds to register as "foreign agents."
In a clear nod to the Pussy Riot stunt, pro-Kremlin lawmakers last week discussed a new bill that would make "offending religious feelings" a crime punishable by up to five years in prison.
Actions like these have left the friends, families, and lawyers of the Pussy Riot women pessimistic about the possibility of a successful appeal.
Violetta Volkova, one of the three lawyers for the women, said Friday after visiting a prison where they are being held that she had little hope for a fair sentence in a country where courts bow to the authorities.
"There is always at least some minimal hope for common sense and that the court will act in accordance with the law," she said. "But given the political situation in Russia, we can't depend on a legal sentence."
Stanislav Samutsevich, the father of one of the women, said he also had little hope, saying that he believed the government would use the appeals process to "in some way justify the severe sentence imposed."
Friends and family say they have tried to keep the women busy with books and letters to try to lighten their mood.
Olga Vinogradova, a children's librarian, book reviewer, and longtime friend of the convicted Maria Alekhina, sent her philosophy books to read. She said she received messages from Alekhina once or twice a week.
Like Tolokonnikova, Alekhina is the mother of a young child, a 5-year-old boy, a fact which has drawn particular sympathy from supporters of the women, who have been behind bars since their arrest in March.
"One thing that she wrote to me in a letter is that . she couldn't pay a higher price than such a long separation from her child," said Vinogradova. "For her freedom to speak her mind that is the greatest price."
Vinogradova said that in her exchanges with Alekhina her friend had expressed little hope of leaving with an effective appeal.
"She's scared about what's happening now, with the new laws," said Vinogradova, "I think she may have expected more from the protest movement."
____
Vladimir Isachenkov contributed to this report.
Source: http://news.yahoo.com/russian-church-pussy-riot-deserve-mercy-repent-132710537.html
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